Bruker Daltonics and Isis in Biosensor Alliance

A new alliance between Bruker Daltonics (Billerica, MA, USA), a subsidiary of Bruker BioSciences, and Isis Pharmaceuticals (Carlsbad, CA, USA) has been announced for the manufacturing and distribution of a new Ibis T5000 biosensor system. This universal biosensor system can simultaneously identify thousands of types of infectious organisms in a sample.

Under the terms of the agreement, Bruker Daltonics will be the exclusive worldwide manufacturer of the Ibis T5000 biosensor system, which incorporates Bruker Daltonics' microtof electrospray ionization (esi)-tof (time of flight), or ESI-TOF, mass spectrometer. Bruker Daltonics will also be responsible for order processing, system installations, and service in North America, Europe and the Middle East. In Europe and the Middle East, Bruker Daltonics will have exclusive rights to sell Ibis T5000 systems and Ibis infectious organism identification kits for various government applications, and will have non-exclusive rights to sell to all other customers. Outside of Bruker Daltonics' exclusive market, Isis may sell Ibis T5000s and its infectious organism identification kits.

The Ibis T5000 utilizes the triangulation identification for the genetic evaluation of risks (TIGER) methodology, which is a combination of genomics, mathematical modeling, mass spectrometry, and molecular amplification to generate a "fingerprint” of each bacterium or virus, allowing it to identify virtually any bacteria or virus present in a sample. The Ibis T5000 biosensor system can rapidly identify or classify organisms that are newly-emerging, genetically altered, or unable to be cultured. The Ibis T5000 biosensor works with many different types of infectious samples from human samples, such as throat swabs or sputum, and environmental samples, such as soil or air.

Ibis plans to commercialize the Ibis T5000 biosensor system and associated reagents to government customers for use in biowarfare defense, epidemiologic surveillance, and forensics; and to non-government customers for use in pharmaceutical process control, hospital-associated infection control, and infectious disease diagnostics. The Ibis T5000 is currently designated for research use only (RUO) and has not yet been approved for any regulated uses, including in vitro diagnostics.

Bruker Daltonics develops innovative life science tools based on mass spectrometry, and also offers a broad line of nuclear, biologic and chemical detection products for homeland security.



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Bruker Daltonics
Isis Pharmaceuticals