New "Virus Sponge” Could Improve Flu Treatments

An inexpensive hydrogel sponge that filters a patient's blood could remove influenza virus H5N1from the patient's body.

Researchers at the University of Maryland (College Park, USA) created the sponge based on a technology called molecular imprinting. In molecular imprinting, researchers stamp a molecule's shape into a substance, in this case, the sponge-like hydrogel. When the specific molecule filters through the hydrogel, it fits in the imprint hole and is trapped. The process could also be used to make vaccine production more efficient, and could be shaped into a pill that could reduce glucose levels in diabetics, among other applications.

Researchers so far used the technique on plant viruses and human parvovirus B19 (which causes fifth disease in babies), and have begun work on the H5N1 influenza virus. Another potential application is to use the material as a filter in masks for those needing protection in case of biologic warfare or other harmful biologic agent exposure.

"This new technology could be integrated into hospitals and healthcare centers at minimal cost,” said lead author Peter Kofinas, Ph.D., a professor in the department of bioengineering. "This virus removal device can be used the same way as a kidney dialysis machine. If you have a viral infection, you can go to the hospital and have your blood cleaned of that virus.”


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