Area Decontamination Technology Protects Against HAIs

An automated decontamination solution provides a safe, effective, and convenient method for the control of environmental pathogens.

The Glosair automated area decontamination solution is designed for small (10 m³) to large (200 m³) spaces in environments such as hospitals and healthcare facilities, and is intended for regular use as part of an infection prevention program that includes traditional manual cleaning methods. The 48-kg device is wheeled into a room and put on an automated cycle; a 5%–6% hydrogen peroxide (H₂O₂) mist is then dispersed to decontaminate hospital areas, including high-touch, hard-to-reach, and hidden areas, without leaving wet residues. The mist also contains a low dose of silver cations that contribute to inactivation by inhibition of pathogen protein synthesis.


The unique combination of H₂O₂ and silver cations provides an effective dual mechanism for the destruction of microorganisms involved in hospital acquired infections (HAIs). Studies have shown that the GLOSAIR system is effective against a broad range of pathogens, including bacteria, fungi, and spores, and in a range of different healthcare environments. The GLOSAIR automated area decontamination system is a product of Advanced Sterilization Products (ASP; Irvine, CA, USA). The decontamination solution is provided in sealed cartridges that lock into place, without exposing hospital staff to H₂O₂.

“Think of it as a hard-case golf bag. Inside, hydrogen peroxide at five per cent is aerosolized to create a mist,” said Brian Langer, former research and development director at ASP. “The nozzle shoots out compressed air, then the hydrogen peroxide is introduced, a bit like a carburetor on a car.”

H₂O₂ is a strong oxidant that is most often used to sterilize heat or temperature sensitive articles such as rigid endoscopes. The biggest advantage of H₂O₂ as a sterilant is the short cycle time, but there are also drawbacks, such as material compatibility issues. For example, paper products cannot be sterilized due to a process called cellulostics, in which the H₂O₂ is completely absorbed by the paper product.

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