Combination Therapy Device Hastens Wound Healing

A non-invasive, portable device combines the benefits of therapeutic ultrasound with electrostimulation to heal chronic ulcers, reduce lesion size and wound pain, and accelerate tissue regrowth.

The BRH Medical (Jerusalem, Israel) BRH-A2 device implements a combination of therapeutic ultrasound and electrostimulation in modulating cycles of independent and joint activity in order to create a micro-circulation effect, providing in essence a massage-like process within the tissues and blood vessels of the impacted medium that increases blood flow to cellular structures, modifying the direction of cellular and subcellular aggregation, and as a result rapidly increasing the healing rate. The portable system can be used together with any treatment modality.


The BRH-A2 system includes proprietary integrated user-friendly software that provides detailed patient data, including specific data regarding the location, type, and characteristics of specific wounds, which can be saved for improved patient management. Using algorithms, the device can accurately measure ulcer size, even while the edges may not be clearly defined due to loss of tissue. The system, which has been approved by the U.S. Food and Drug Administration (FDA), also stores individual clinical data on thousands of patients for efficient treatment and follow-up procedures.

“The market for products that ease the pain of chronic wounds is large and growing. Our vision is to become the gold standard for treatment of chronic wounds of all kinds, including pressure wounds, diabetic leg wounds, and wounds caused as a result of ischemia,” said Motti Oderberg, CEO of BRH Medical. “We are now exploring the most efficient way to penetrate the market, and are currently focusing on identifying strategic partnerships.”

Electrostimulation is known to pull taut fibroblasts and resultant collagen, yielding a stronger weave; in addition, a proven effect of ultrasound is stimulating fibroblasts to create collagen, and also inducing the new collagen to lay out in a more ordered pattern, resulting in a better weave for epithelialization. The end result of combining the two technologies is a more ordered and tighter collagen weave.

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