Lumbar Catheter Treats CNS Disorders

A new lumbar catheter is designed to drain cerebrospinal fluid (CSF) from the space surrounding the spinal cord as part of a drug delivery system used to treat subarachnoid hemorrhage, spinal cord injury, traumatic brain injury, and stroke. The catheter has been cleared by the US Food and Drug Administration (FDA).

This system perfuses the brain and spinal cord with a proprietary, artificial CSF known as NeurySol, in order to rapidly remove neurotoxins from the brain or spinal cord and to deliver therapeutic agents directly to the central nervous system. Preclinical studies have demonstrated that NeurySol can remove blood from the space surrounding the brain following subarachnoid hemorrhage to reduce the amount of ischemia or swelling that results after an injury to the brain or spinal cord. They also showed that NeurySol could improve the function of animals with spinal cord injuries. A multicenter trial involving patients with subarachnoid hemorrhage is now under way.

The new catheter and the NeurySol system were developed by Neuron Therapeutics, Inc. (Malvern, PA, USA), a company focused on developing new drugs and medical devices for disorders of the central nervous system.




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