Automated Test for Troponin-I

A test for troponin-I (TnI) is now available for use on the automated Architect i2000SR immunoassay system and the Architect ci8200 immunochemistry system of Abbott Laboratories (Abbott Park, IL, USA). The test has been cleared by the U.S. Food and Drug Administration (FDA).

Troponins are a complex of regulatory proteins present on striated muscle that regulate the calcium-mediated interaction of actin and myosin. TnI is a protein released from dead or severely injured heart muscle cells following a cardiac event. Providing stat results within 18 minutes, the Architect i2000SR can perform up to 200 tests per hour. The stat functionality enables rapid turnaround time of TnI results, enabling doctors to quickly diagnose and treat patients with chest pain.

"Based on the American College of Cardiology's new criteria for diagnosing myocardial infarction, troponin has become the gold standard in diagnostic testing,” noted Michael S. Parmacek, M.D., chief of cardiovascular medicine, University of Pennsylvania (Philadelphia, USA).

Combining immunoassay and clinical chemistry on one integrated platform, the ci8200 system runs up to 200 immunoassay tests and up to 1,200 clinical chemistry tests an hour. By consolidating both testing capabilities, the ci8200 helps improve laboratory productivity and efficiency. When running tests to aid the diagnosis of chest pain, tests can be run concurrently, supplying doctors with the rapid results they need to diagnose a potential cardiac event and determine the best course of treatment.




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