Test Measures Three Levels of Estradiol

A new improved test for estradiol is a chemiluminescent microparticle immunoassay (CMIA) that provides an initial result in 29 minutes.

The test, designed for use on the Architect systems of Abbott Laboratories (Abbott Park, IL, USA), measures low, medium, and high concentration levels of estradiol. The company notes that estradiol testing can be useful for a variety of conditions, including early or delayed puberty, and can also play an important role in the treatment of infertility. The Architect i2000 and i2000SR systems can process up to 200 immunoassay tests an hour without compromising test throughput or turnaround time.

"The Architect estradiol test was designed to be sensitive and specific, providing precise results across the entire assay range,” noted William Brown, Ph.D., vice president, diagnostic assays and systems development, Abbott Laboratories. "In addition, Architect estradiol has excellent correlation to the ‘gold standard' gas chromatography mass spectrometry (GC-MS) testing. This correlation supports the excellent functional sensitivity and accuracy of the assay.”

Estradiol levels vary, depending on the condition being treated. Levels are usually low in children and men, but in women the levels rise and fall during the normal menstrual cycle. Thus, a diagnostic test has to be able to provide precise results across a wide measurement range.


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