Software Measures Platelet Fraction

Specialized master software programs are designed to assist with the diagnosis and treatment of altered platelet and red-cell production.

More specifically, the software is designed to measure immature platelet fraction (IPF) and reticulocyte hemoglobin equivalent (RET-He) on the XE-2100 hematology analyzers of Sysmex Corp. (Kobe, Japan; www.sysmex.co.jp). All of the cells sampled on the X-series of instruments are exposed to fluorescent dyes with affinity for nucleic acids.

"The Immature Platelet Fraction is an index of thrombopoiesis,” said Ian Giles, M.D., medical director, Sysmex America. "It can determine the origin of thrombocytopenia by helping to distinguish between bone marrow failure and peripheral platelet consumption or destruction.”

The RET-He parameter provides a direct measurement for the mean reticulocyte hemoglobin content in picograms. It is therefore a useful parameter for the early diagnosis of iron deficiency (iron restricted erthropoiesis) and for optimizing iron therapy.

"Release of the new master software programs for the XE-2100 indicates Sysmex's commitment to our ongoing improvement of XE-2100 fluorescent flow cytometry technology,” said Peggy Barranco, product manager, Sysmex America. The Sysmex XE-2100 is now in more than 6,000 laboratories worldwide.




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