Test Determines Genetic Resistance to HIV

A test has been developed that determines if a person is a fast, neutral, or slow progressor to AIDS after human immunodeficiency virus (HIV) infection.

The results of the test help individuals infected with HIV know how quickly the virus is likely to cause disease, enabling physicians to decide how aggressive the therapy needs to be for each patient.

The test was developed by Independent Forensics (Jersey City, NJ, USA). It measures the genetics of CCR5 receptors on T-cells and uses a simple buccal swab collection procedure, which can be easily carried out at home. Test results are available in three weeks. CCR5 is the primary HIV receptor in T-cells, and people contain varying amounts of this receptor according to their genetic make-up. The fewer available CCR5 receptors people have, the more likely it is that they will demonstrate a slow progression to AIDS when infected with HIV-1.

"We believe the CCR5 halotype test is one of the most important things an individual with HIV can do to help in their treatment. It is part of our philosophy to 'Know Thyself', knowing your own genetic makeup will help everyone make informed and healthy life decisions,” explained Jack Keehma, CEO of Independent Forensics.

Independent Forensics' services include paternity, immigration, Codis data basing, casework, expert witness testimony, and product development for the forensic community. The company's products include SampleTrak software and rapid-stain identification tests for saliva and semen.



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