High-Throughput Automated HBV Assays
By HospiMedica staff writers
Posted on 27 Mar 2003
A complete panel of high-throughput automated assays for hepatitis B virus (HBV) is now available. Posted on 27 Mar 2003
The panel includes HbsAg, a 29-minute assay offering a sensitivity of 0.01 ng/ml; Anti-HBs, an 18-minute assay offering linear measurement between 1 and 1,000 mIU/ml; HBCoreTotal, an antigen-bridging assay using a chaotrope to remove nonspecific binding, with a specificity of 99.9% and throughput of 120 tests per hour; HBCorelgM, an M antibody capture assay with 100% clinical specificity and throughput of 120 tests per hour. The assays are from Bayer Diagnostics (Leverkusen, Germany).
The assays are designed to run on the Bayer's Advia Centaur immunoassay system. The Centaur is a random-access system that can process a full range of infectious disease serology and therapeutic drug monitoring (TDM) assays at the highly productive rate of up to 240 tests per hour. Bayer states that the Advia's superior assay performance is achieved through the use of state-of-the-art chemiluminescence technology.
"HBV is the latest disease state assay group to be added to the system's menu, complementing the Toxoplasma and Rubella IgG and IgM assays, which are already well established, together with TDM methods for gentamicin, vancomycin, and tobramycin,” said Alistair Gammie, of Bayer Diagnostics.
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