Leptin Soluble Receptor Elisa
By HospiMedica staff writers
Posted on 30 Apr 2003
A new two-site enzyme-linked immunosorbent assay (ELISA) is highly specific for the soluble, extracellular portion of the human leptin receptor, allowing a true measurement of circulating levels without cross-reactivity or interference with leptin.Posted on 30 Apr 2003
The one-step assay offers 3.5 hours turn-around-time and is easily automated. There is no detectable cross-reactivity or interference with human recombinant leptin. The assay is suitable for use with serum or plasma. No sample treatment is required and reagents are ready to use.
Leptin has a role in many diverse physiologic processes, especially obesity but also energy homeostasis, inflammation, angiogenesis, hematopoiesis, immune function, and reproduction, according to studies. Leptin circulates either as a free hormone or bound to specific binding proteins, the most abundant being the extracellular portion of the specific leptin receptor. The assay is the product of Diagnostic Systems Laboratories, Inc. (DSL, Webster, TX, USA).
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