Surgical Sealant Prevents Leaks

A new surgical sealant is designed to prevent air and fluid leaks following lung, gastrointestinal, and cardiovascular surgery.

Air and fluid leaks following surgery are a common source of complications that often lead to further surgery. The new sealant is applied following closure of tissues with sutures or staples. The sealant is sprayed over the incision by a simple dual-syringe applicator. In less than a minute, a tough, flexible barrier is formed that strongly adheres to the tissue being repaired. As the tissue heals, the sealant gradually resorbs. The sealant was developed by Protein Polymer Technologies, Inc. (PPTI, San Diego, CA, USA).

"The performance demonstrated with this new product is an exciting milestone in the continuing commercial development of our core tissue adhesive technology,” said Donald S. Kaplan, Ph.D., president and chief operating officer. "The accomplishments of our product development team clearly demonstrate the breadth of capabilities of this technology.”

PPTI has been a pioneer in protein design and synthesis, creating an extensive portfolio of proprietary biomaterials for use in the development of bioactive devices. These genetically engineered biomaterials are high-molecular-weight proteins, processed into products with physical and biologic characteristics tailored to specific clinical performance requirements.




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