Fibrin Matrix for Bone Voids

Voids or gaps in bone that are not intrinsic to the stability of the bony structure, including bone defects from surgery or traumatic injury, can be repaired with a new bone filler.

TricOs T, manufactured by Baxter Healthcare (Deerfield, IL, USA), is a proprietary combination of hydroxyapatite-coated beta tricalcium phosphate (HA/TCP) granules and a fibrin matrix. It is intended to be packed into bony voids or gaps of the skeletal system (i.e., the extremities, spine, and pelvis). The product has received marketing clearance from the U.S. Food and Drug Administration (FDA).

The bone filler provides a three-dimensional osteoconductive environment for the formation of new bone. The fibrin matrix enhances the handling of the product by making it moldable and allows it to hold its shape. It has no initial mechanical properties, and therefore rigid fixation techniques are recommended. Over time, TricOs T is resorbed and replaced by bone.

"TricOs T is an alternative technology to harvesting bone from the patient in certain spinal and orthopedic surgeries,” said Gordon Sutherland, general manager of Baxter's BioSurgery business. "Early users of this technology have stated that they like the handling characteristics of the product as it is very easy to mold into the correct shape to fit the bone defect.”




Related Links:
Baxter Healthcare