Acellular Collagen Matrix for Abdominal Wall Repair

A biologic matrix offers a successful alternative to synthetic materials in surgical soft tissue reinforcement of abdominal hernias.

XenMatriX is a non-crosslinked porcine dermal matrix designed for soft tissue reconstruction in the treatment of abdominal wall (hernia) repair where the connective tissue has ruptured. The acellular dermal matrix employs a patented technology that maintains a structurally intact scaffold for enhanced biocompatibility in the host tissue. This naturally facilitates tissue regeneration by encouraging revascularization and repopulation of host cells, while minimizing the risks of encapsulation by fibrotic tissue and generating a minimal inflammatory response. XenMatriX is ready for implantation and does not require rehydration, and is available in extra large sizes, which eliminates the need for quilting multiple pieces together, minimizing concerns of suture pullout and resultant recurrence. XenMatriX, which has already been implanted successfully in urological and gynecological procedures, is manufactured by Brennen Medical (St. Paul, MN, USA), and has now been approved by the U.S. Food and Drug Administration (FDA) for abdominal hernia repair as well.

"We are extremely pleased with the outcomes of XenMatriX. Unlike traditional mesh products, XenMatriX can be used successfully in contaminated or potentially contaminated and complex fields,” said Phillip Lawin, President of Brennen Medical. "This provides patients and surgeons a truly safe and effective alternative for abdominal wall hernia repair.”

XenMatriX is engineered to meet the performance requirements for most abdominal wall reinforcement procedures, including traumatic fascia loss, potentially contaminated surgical fields, infected mesh replacement, parastomal hernia repair, ventral hernia repair, and in patients with high-risk comorbidities such as morbid obesity, diabetes, and other underlying diseases.

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Brennen Medical