Implant Pouch Creates Vascularized Tissue Pocket

A new envelope made from extracellular matrix (ECM) creates a stable environment for cardiac implantable electronic devices (CIEDs).

The CorMatrix CanGaroo ECM envelope is constructed from a multi-laminate sheet of decellularized, non-crosslinked, lyophilized ECM derived from porcine small intestinal submucosa, which serves as a bioscaffold for vascular ingrowth from adjacent tissues delivering progenitor cells and nutrients to the matrix, which then differentiate into tissue-specific cells and structures. The ECM material is naturally degraded and resorbed, gradually replaced by the patient’s own cells, leaving remodeled functional tissue where damaged or injured tissue would normally be expected.


The ECM envelope, which is provided in four different sizes, is intended to hold an array of device types and sizes, such as pacemakers, cardiac resynchronization therapy (CRT) devices, or implantable cardioverter defibrillators (ICDs), after the surgical procedure has been completed. The CorMatrix CanGaroo ECM Envelope is a product of CorMatrix (Rosewell, GA, USA), and has been approved by the U.S. Food and Drug Administration (FDA).

“The CorMatrix CanGaroo was designed to address the needs described to us by physicians implanting CIED’s in their daily practice,” said John Davis, executive vice president of sales and marketing at CorMatrix. “We are pleased that we can provide a device that our physician’s requested to address complications with CIED implantation.”

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