Fast Vascular Sealant to Prevent Blood Leakage

A new completely synthetic vascular sealant is a self-polymerizing gel for sealing around vascular reconstructions and incision lines to prevent blood leakage. The sealant has been cleared by the US Food and Drug Administration (FDA).

The sealant, called CoSeal, consists of two synthetic liquids designed to self-polymerize within seconds at the site of application, forming a flexible hydrogel seal without the need for primer coats or additional equipment, such as a light source to activate the product. The current standard for vascular sealing is to apply manual pressure to the graft site or to wait for a clot to occur, sometimes taking up to 30 minutes or longer to achieve, says CoSeal's developer, Cohesion Technologies (Palo Alto, CA, USA). Since CoSeal is a mechanical barrier to leakage that does not interfere with the clotting cascade, it works in patients with normal or compromised coagulation, such as those on heparin.

"CoSeal provides surgeons with a safe and effective method for vascular sealing that may minimize complications, reduce surgery times, and improve patient outcomes,” said William G. Mavity, president and CEO of Cohesion Technologies.




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