We use cookies to understand how you use our site and to improve your experience. This includes personalizing content and advertising. To learn more, click here. By continuing to use our site, you accept our use of cookies. Cookie Policy.

Coaptation Products Aid Tensionless Repair of Severed Nerves

By HospiMedica International staff writers
Posted on 15 May 2013

Image: The AxoGuard Nerve Connector and Nerve Protector (Photo courtesy of AxoGen).

Image: The AxoGuard Nerve Connector and Nerve Protector (Photo courtesy of AxoGen).

Two products derived from porcine submucosa extracellular matrix (ECM) allow close approximation of severed peripheral nerves and provide protection during the healing process.

The AxoGuard Nerve Connector is a tubular, multilaminar ECM product with an open lumen in which the severed nerve ends are placed, typically used to align and connect nerves with less than a 5 mm gap between the severed ends. The AxoGuard Nerve Connector material allows the body's natural healing process to repair the nerve by isolating and protecting it during the healing process, letting autologous cells incorporate into the ECM and remodel and form a tissue similar to the nerve epineurium.

The AxoGuard Nerve Protector is a multilaminar ECM that is used to wrap and protect injured peripheral nerves and reinforce coaptation sites after surgery, isolating the nerve during the healing process and preventing soft tissue attachments. Similarly, the patient's own cells incorporate into the ECM to remodel and form a tissue similar to the nerve epineurium. It is provided sterile, for single use only, and in a variety of sizes to meet the surgeon’s needs. Both the Nerve Protector and Nerve Connector are products of AxoGen (Alachua, FL, USA), and have received the European Union CE marking.

“The CE Mark approval for AxoGuard Nerve Protector and AxoGuard Nerve Connector is a significant milestone in our effort to expand availability of the AxoGen family of products to Europe and is an important step in our growth strategy,” said Karen Zadere, CEO of AxoGen. “We believe these products will be well received to treat a wide variety of peripheral nerve injuries from simple lacerations of the finger to complex extremity reconstructions.”

Related Links:

AxoGen

Visit expo >

Gold Member

12-Channel ECG

CM1200B

Antipsychotic TDM Assays
Saladax Antipsychotic Assays

New

Medical Adhesive

MED 5570U

New

Immobilization System

Cranial 4Pi Immobilization

Latest Surgical Techniques News

Channels

Artificial Intelligence

view channel

AI Analysis of Pericardial Fat Refines Long-Term Heart Disease Risk

Accurately identifying long-term cardiovascular disease risk in asymptomatic adults remains challenging for clinicians. Missed or underestimated risk delays preventive therapy and increases the chance... Read more

Machine Learning Approach Enhances Liver Cancer Risk Stratification

Hepatocellular carcinoma, the most common form of primary liver cancer, is often detected late despite targeted surveillance programs. Current screening guidelines emphasize patients with known cirrhosis,... Read more

Image: connected devices offer new possibilities in the early detection of abnormalities or changes in brain health (Photo courtesy of 123RF)

New AI Approach Monitors Brain Health Using Passive Wearable Data

Brain health spans cognitive and emotional functions and can fluctuate even in adults without diagnosed disease. Detecting early changes remains difficult in routine care and burdens specialty services... Read more

$Image: Study procedure flow chart. After patients with BSI were identified from microbiology databases, 27 patients\' characteristics were extracted from electronic health records. After the dimension of those variables was reduced with Uniform Manifold Approximation and Projection (UMAP), k-means++ was used to identify clusters. Three clinically distinct clusters were identified. Among those clusters, patients were divided into solid organ transplant (SOT) and non-SOT groups. Clinical characteristics and outcomes were evaluated (Masayuki Nigo et al., American Journal of Transplantation (2026). DOI: 10.1016/j.ajt.2025.10.019)$

AI Tool Maps Early Risk Patterns in Bloodstream Infections

Bloodstream infections can deteriorate rapidly and carry high mortality, especially in immunocompromised patients. Clinicians need reliable early risk stratification to prioritize monitoring and organ support.... Read more

Critical Care

view channel

Noninvasive Monitoring Device Enables Earlier Intervention in Heart Failure

Hospitalizations for heart failure with preserved ejection fraction (HFpEF) remain common because lung congestion often worsens before symptoms prompt treatment changes. Missed early decompensation... Read more

Automated IV Labeling Solution Improves Infusion Safety and Efficiency

Medication administration in high-acuity settings is often complicated by multiple concurrent infusions, making accurate line identification essential. In a 10-hospital intensive care unit study, 60% of... Read more

First-Of-Its-Kind AI Tool Detects Pulmonary Hypertension from Standard ECGs

Pulmonary hypertension is a progressive, life‑threatening disease that is frequently missed early because symptoms such as dyspnea are nonspecific and diagnostic delays can exceed two years.... Read more

Routine Blood Pressure Readings May Identify Risk of Future Cognitive Decline

Hypertension is a major contributor to vascular aging and dementia, yet routine clinical workflows rarely flag neurocognitive risk early. Identifying patients at risk before symptoms appear could support... Read more

Patient Care

view channel

Wearable Sleep Data Predict Adherence to Pulmonary Rehabilitation

Chronic obstructive pulmonary disease (COPD) is a long-term lung disorder that makes breathing difficult and often disturbs sleep, reducing energy for daily activities. Limited engagement in pulmonary... Read more

Image: The revolutionary automatic IV-Line flushing device set for launch in the EU and US in 2026 (Photo courtesy of Droplet IV)

Revolutionary Automatic IV-Line Flushing Device to Enhance Infusion Care

More than 80% of in-hospital patients receive intravenous (IV) therapy. Every dose of IV medicine delivered in a small volume (<250 mL) infusion bag should be followed by subsequent flushing to ensure... Read more

Image: A screengrab from the VR training module that shows invisible contamination on portable medical equipment (Photo courtesy of Mass General Brigham)

VR Training Tool Combats Contamination of Portable Medical Equipment

Healthcare-associated infections (HAIs) impact one in every 31 patients, cause nearly 100,000 deaths each year, and cost USD 28.4 billion in direct medical expenses. Notably, up to 75% of these infections... Read more

Image: The portable biosensor platform uses printed electrochemical sensors for the rapid, selective detection of Staphylococcus aureus (Photo courtesy of AIMPLAS)

Portable Biosensor Platform to Reduce Hospital-Acquired Infections

Approximately 4 million patients in the European Union acquire healthcare-associated infections (HAIs) or nosocomial infections each year, with around 37,000 deaths directly resulting from these infections,... Read more

Health IT

view channel

mage: The EHR–driven tool could help doctors intervene earlier to protect transplanted kidneys (Photo courtesy of 123RF)

EMR-Based Tool Predicts Graft Failure After Kidney Transplant

Kidney transplantation offers patients with end-stage kidney disease longer survival and better quality of life than dialysis, yet graft failure remains a major challenge. Although a successful transplant... Read more

Image: A wearable sweat sensor based on the core–shell nanoparticle technology (Photo courtesy of Caltech)

Printable Molecule-Selective Nanoparticles Enable Mass Production of Wearable Biosensors

The future of medicine is likely to focus on the personalization of healthcare—understanding exactly what an individual requires and delivering the appropriate combination of nutrients, metabolites, and... Read more

Image: Smartwatches could provide more affordable and accessible cardiac monitoring (Photo courtesy of 123RF)

Smartwatches Could Detect Congestive Heart Failure

Diagnosing congestive heart failure (CHF) typically requires expensive and time-consuming imaging techniques like echocardiography, also known as cardiac ultrasound. Previously, detecting CHF by analyzing... Read more

Image: Schematic diagram of a wireless, skin-contact system that simultaneously measures biosignals and delivers drugs (Photo courtesy of DGIST)

Versatile Smart Patch Combines Health Monitoring and Drug Delivery

As the global population ages, the need for personalized healthcare is becoming increasingly important. This shift has fueled a growing interest in wearable medical devices that can provide real-time health... Read more

Point of Care

view channel

Image: The Nevisense uses a non-invasive procedure that combines EIS technology with AI to provide in-depth skin analysis (photo courtesy of SciBase)

AI-Enabled Platform Supports Clinical Decision-Making in Melanoma Detection

Visual examination remains the foundation of dermatologic assessment for suspicious skin lesions, and many dermatologists are confident using clinical and dermoscopic techniques. However, studies show... Read more

Business

view channel

GE HealthCare Leads Major European Initiative to Advance Cardio-Oncology Care

Cardiovascular complications are increasingly recognized among people undergoing or recovering from cancer treatment, driven by pre‑existing disease and the cardiotoxic effects of chemotherapy, radiotherapy,... Read more

Medtronic and GE HealthCare Broaden Alliance Across Monitoring and Care Solutions

Medtronic announced a multiyear renewal and significant expansion of its global strategic alliance with GE HealthCare across Patient Care Solutions. Building on more than three decades of collaboration,... Read more

Image: NeuWave’s microwave ablation system is used in percutaneous tumor ablation procedures (photo courtesy of NeuWave Medical)

Quantum Surgical Acquires NeuWave from Johnson & Johnson

Quantum Surgical announced that it has acquired NeuWave Medical from Johnson & Johnson. NeuWave’s microwave ablation system is used in percutaneous tumor ablation procedures, and the acquisition supports... Read more

Image: Medtronic’s intent to acquire CathWorks follows a 2022 strategic partnership with a co-promotion agreement for the FFRangio System (Photo courtesy of CathWorks)

Medtronic to Acquire Coronary Artery Medtech Company CathWorks

Medtronic plc (Galway, Ireland) has announced that it will exercise its option to acquire CathWorks (Kfar Saba, Israel), a privately held medical device company, which aims to transform how coronary artery... Read more