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Image: A normal blood vessel, shown at top, is compared with a blood vessel affected by excess bradykinin (Photo courtesy of Oak Ridge National Laboratory)

Supercomputer Analyzes Lung Fluid Cells from Coronavirus Infected Patients to Repurpose Drugs for COVID-19 Treatment

Analyses of lung fluid cells from COVID-19 patients conducted on the fastest supercomputer in the US suggests that gene expression patterns may explain the runaway symptoms produced by the body’s response to SARS-CoV-2 and has led to the discovery of at least 10 existing drugs that are known to act on the specific pathways. More...
03 Sep 2020
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Sanofi and Regeneron Halt Further Clinical Studies for Kevzara in COVID-19 After Disappointing Phase 3 Trial Results

Sanofi S.A. (Paris, France) and Regeneron Pharmaceuticals, Inc. (Tarrytown, NY, USA) have decided to discontinue further clinical studies for Kevzara (sarilumab) in COVID-19 after suffering a setback in the drug’s Phase 3 trial. More...
02 Sep 2020
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Immunologists Receive Multi-Million Funding Boost to Research Role of Immune System in COVID-19

Immunologists from The University of Edinburgh (Edinburgh, Scotland) have received a multimillion pound funding boost to research the role of the immune system in COVID-19. More...
02 Sep 2020
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NIH Sets up Centers for Research in Emerging Infectious Diseases for Rapid Responses to New Viruses Like SARS-CoV-2

The National Institutes of Health (NIH Bethesda, MA, USA) has established the Centers for Research in Emerging Infectious Diseases (CREID), a global network that will involve multi-disciplinary investigations into how and where viruses such as SARS-CoV-2 and other pathogens emerge from wildlife and spillover to cause disease in people. More...
02 Sep 2020
Image: AstraZeneca Begins Phase 3 Trial of COVID-19 Vaccine and Expands Supply Agreement with Oxford Biomedica (Photo courtesy of AstraZeneca).

AstraZeneca Begins Phase 3 Trial of COVID-19 Vaccine and Expands Supply Agreement with Oxford Biomedica

AstraZeneca (Cambridgeshire, England) has begun Phase 3 clinical trial of its COVID-19 vaccine candidate AZD1222 that will enroll up to 30,000 adults aged 18 years or over in the US to assess its safety, efficacy and immunogenicity. More...
02 Sep 2020
Image: A microfluidic cartridge for a 30-minute COVID-19 test (Photo courtesy of Bill King)

New Portable, 30-Minute COVID-19 Test Could Enable Diagnosis at POC Without Need for Laboratory

Researchers have demonstrated a prototype of a rapid COVID-19 molecular test and a simple-to-use, portable instrument for reading the results with a smartphone in 30 minutes, which could enable point-of-care diagnosis without needing to send samples to a lab. More...
02 Sep 2020
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Nasopharyngeal and Oropharyngeal Swabs Detect More COVID-19 Cases than Saliva Testing in New Study

A new study by Canadian researchers has found that nasopharyngeal and oropharyngeal swabs can detect more COVID-19 cases than saliva testing. More...
01 Sep 2020
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