Critical Care



First Vaccine Developed Against Toxic Shock Syndrome
Developed by researchers at MedUni Vienna (Austria) and Biomedizinische Forschungs (Vienna, Austria), the recombinant toxic shock syndrome toxin-1 variant (rTSST-1v) vaccine was developed from a detoxified Staphylococcus toxin. To test the vaccine, the researchers conducted a randomized phase I first-in-human trial in 46 healthy adults aged 18-64 years. The participants were randomly assigned to receive increasing doses of rTSST-1v or an adjuvant placebo of aluminium hydroxide (Al(OH)3). More...12 Jul 2016


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