Next Gen Digital Diagnostic Platform to Detect Multiple Pathogens within 5 Minutes at Gene Level
|
By HospiMedica International staff writers Posted on 30 Jun 2023 |
|
An advanced digital diagnostic platform with the capability to detect multiple pathogens in five minutes at the molecular gene level and priced significantly lower than current molecular tests is all set to disrupt the PCR market.
Check4 by IdentifySensors Biologics (Cleveland, OH, USA) is a next-generation digital diagnostic platform that has been developed to detect the genetic material of a wide range of pathogens for over-the-counter and point-of-care use. The Check4 testing platform comprises two components: a reusable Bluetooth reader roughly the size of a mobile phone, and disposable test cartridges that connect to the reader. Each test sample can simultaneously detect up to three different pathogens. Digital graphene sensors within the cartridges target conserved regions of the genome, thereby ensuring high sensitivity and specificity without the need for enzymatic amplification or reagents.
The sensors in the disposable cartridges can be customized to identify a broad range of pathogens that display similar symptoms. Multiplex tests are in development for respiratory pathogens (COVID, RSV, and influenza), gastrointestinal pathogens (Norovirus, Rotavirus, and Adenovirus), and sexually transmitted pathogens (HIV, Hepatitis, Chlamydia, Gonorrhea, and Herpes). Other tests under development include those for SEPSIS, MRSA, Lyme disease, and tropical pathogens such as Zika, Dengue, Yellow Fever, and West Nile virus. Previous research indicates that Check4 can potentially diagnose infections like COVID, RSV, and influenza even before patients exhibit symptoms. IdentifySensors has commenced testing this novel diagnostic device in anticipation of FDA submissions. Clinical studies for the Check4 diagnostic device are slated for this year as part of an extensive testing platform designed to be adapted for detecting a broad range of additional pathogens in the coming years.
"In preliminary studies we have seen encouraging results of this new technology," said Greg Hummer M.D., IdentifySensors co-founder and CEO. "We are excited to test these devices and move forward with additional targets that detect a wide range of infections."
Related Links:
IdentifySensors Biologics
Latest Point of Care News
Channels
Critical Care
view channel
AI Model Analyzes Patient Data to Diagnose Multiple Sclerosis With 90% Accuracy
Multiple sclerosis (MS) is a chronic inflammatory condition affecting the central nervous system. Most patients initially experience the relapsing-remitting form (RRMS), characterized by periods of symptom... Read more
Magnetically Navigable Microparticles Enable Targeted Drug Delivery
Abdominal aortic aneurysms (AAA) can be life-threatening if not treated and result in nearly 10,000 deaths annually. Researchers working to improve treatments for AAA could now make it possible for doctors... Read more
AI-Powered Algorithm Automates Analysis of Coronary Stents After Implantation
Every year, over three million people globally receive stents to open blocked blood vessels caused by heart disease. However, monitoring the healing process after stent implantation remains a significant challenge.... Read more
Surgical Techniques
view channel
DNA Origami Improves Imaging of Dense Pancreatic Tissue for Cancer Detection and Treatment
One of the challenges of fighting pancreatic cancer is finding ways to penetrate the organ’s dense tissue to define the margins between malignant and normal tissue. Now, a new study uses DNA origami structures... Read more
Pioneering Sutureless Coronary Bypass Technology to Eliminate Open-Chest Procedures
In patients with coronary artery disease, certain blood vessels may be narrowed or blocked, requiring a stent or a bypass (also known as diversion) to restore blood flow to the heart. Bypass surgeries... Read more
Intravascular Imaging for Guiding Stent Implantation Ensures Safer Stenting Procedures
Patients diagnosed with coronary artery disease, which is caused by plaque accumulation within the arteries leading to chest pain, shortness of breath, and potential heart attacks, frequently undergo percutaneous... Read more
World's First AI Surgical Guidance Platform Allows Surgeons to Measure Success in Real-Time
Surgeons have always faced challenges in measuring their progress toward surgical goals during procedures. Traditionally, obtaining measurements required stepping out of the sterile environment to perform... Read morePatient Care
view channel
Portable Biosensor Platform to Reduce Hospital-Acquired Infections
Approximately 4 million patients in the European Union acquire healthcare-associated infections (HAIs) or nosocomial infections each year, with around 37,000 deaths directly resulting from these infections,... Read more
First-Of-Its-Kind Portable Germicidal Light Technology Disinfects High-Touch Clinical Surfaces in Seconds
Reducing healthcare-acquired infections (HAIs) remains a pressing issue within global healthcare systems. In the United States alone, 1.7 million patients contract HAIs annually, leading to approximately... Read more
Surgical Capacity Optimization Solution Helps Hospitals Boost OR Utilization
An innovative solution has the capability to transform surgical capacity utilization by targeting the root cause of surgical block time inefficiencies. Fujitsu Limited’s (Tokyo, Japan) Surgical Capacity... Read more
Game-Changing Innovation in Surgical Instrument Sterilization Significantly Improves OR Throughput
A groundbreaking innovation enables hospitals to significantly improve instrument processing time and throughput in operating rooms (ORs) and sterile processing departments. Turbett Surgical, Inc.... Read moreHealth IT
view channel
Printable Molecule-Selective Nanoparticles Enable Mass Production of Wearable Biosensors
The future of medicine is likely to focus on the personalization of healthcare—understanding exactly what an individual requires and delivering the appropriate combination of nutrients, metabolites, and... Read more
Smartwatches Could Detect Congestive Heart Failure
Diagnosing congestive heart failure (CHF) typically requires expensive and time-consuming imaging techniques like echocardiography, also known as cardiac ultrasound. Previously, detecting CHF by analyzing... Read more
Business
view channel
Expanded Collaboration to Transform OR Technology Through AI and Automation
The expansion of an existing collaboration between three leading companies aims to develop artificial intelligence (AI)-driven solutions for smart operating rooms with sophisticated monitoring and automation.... Read more
