Implantable Device for Pulmonary Hypertension Reduces Cardiac Workload and Enhances Blood Flow
By HospiMedica International staff writers Posted on 04 Mar 2024 |

Pulmonary hypertension is a severe, progressive disease affecting as many as 70 million people globally. It develops when the walls of the pulmonary arteries become rigid, losing their ability to stretch adequately to manage blood flow. Normally, the pressure in the pulmonary arteries of a healthy individual is relatively low. However, in patients with pulmonary hypertension, this pressure increases, and the vessel walls thicken and narrow, impeding blood flow and diminishing vessel elasticity with each heartbeat. This leads to heightened pressure and additional strain on the right side of the heart. Now, a novel implantable device can mimic the function of the healthy vessels by restoring compliance to the pulmonary vessels, thus enabling the heart to pump more blood for less energy. These can improve the ability to exercise while reducing the burden on the heart.
Aria CV’s (St. Paul, MN, USA) Pulmonary Hypertension System is an implantable gas-filled balloon that is introduced percutaneously and functions in the main pulmonary artery to reduce the excessive workload on the right heart that can cause right heart failure. The device aims to restore the benefits of a healthy pulmonary artery by reducing cardiac workload and increasing blood flow through the lungs. This novel device offers an alternative treatment for patients who continue to be significantly impacted by right heart dysfunction related to pulmonary hypertension, for which there are limited approved therapy options. The first patient has now been successfully implanted with the Gen 2 Aria CV Pulmonary Hypertension System as part of the ASPIRE PH clinical trial. The ASPIRE PH trial is a feasibility study assessing the initial safety, tolerability, and efficacy of the Aria System under the Food and Drug Administration’s (FDA) Early Feasibility Study Program.
“The successful patient implant of the Gen 2 system is a significant milestone in realizing our mission to improve the lives of those suffering from pulmonary hypertension, a life-threatening disease that can lead to heart failure,” said Dan Gladney, President and CEO of Aria CV. “This procedure is a testament to the dedicated ASPIRE PH team that is providing patients with a novel therapeutic option to treat this deadly condition. If approved, this technology has the potential to be lifesaving and life-changing for thousands of patients with pulmonary hypertension.”
Latest Critical Care News
- Novel Coating Significantly Extends Longevity of Implantable Biosensors
- Nanogel-Based Drug Delivery Technology to Improve UTI Treatment
- New IV Pole Improves Safety and Ease of Administering IV Medications at Hospital Bedside
- Battery-Powered Wearable Device Monitors Joint Pain
- Wireless Pacifier Monitors Vitals of NICU Babies Without Need for Painful Blood Draws
- Breakthrough Sensor Technology Tracks Stroke After Effects
- New Study Demonstrates AI-Assisted Detection of Reduced Ejection Fraction
- Novel 3D Adipose Tissue Bioprinting Method to Find Applications in Regenerative Medicine
- Miniaturized Pacemaker for Newborns Found Safe and Effective for Up to Two Years
- World’s First 3D Neural Electrode Uses Soft Actuation Technology to Avoid Nerve Damage
- Smartwatch Algorithm Detects Cardiac Arrest
- Blood-Brain Barrier “Organ Chip” Treats Brain Tumors Unreachable by Chemotherapy
- AI Model Could Use ECG Tests to Detect Premature Aging and Cognitive Decline
- World-First Technology Uses Real-Time ECG Signal Analysis for Accurate CVAD Placement
- AI Outperforms Humans at Analyzing Long-Term ECG Recordings
- Smart Sensor Enables Precise, Self-Powered Tracking of Healing Wounds
Channels
Artificial Intelligence
view channel
Innovative Risk Score Predicts Heart Attack or Stroke in Kidney Transplant Candidates
Heart researchers have utilized an innovative risk assessment score to accurately predict whether patients being evaluated for kidney transplants are at risk for future major cardiac events, such as a... Read more
AI Algorithm Detects Early-Stage Metabolic-Associated Steatotic Liver Disease Using EHRs
Liver disease, which is treatable when detected early, often goes unnoticed until it reaches advanced stages. Metabolic-associated steatotic liver disease (MASLD), the most prevalent form of liver disease,... Read moreSurgical Techniques
view channel
Easy-To-Apply Gel Could Prevent Formation of Post-Surgical Abdominal Adhesions
Surgical adhesions are a frequent and often life-threatening complication following open or laparoscopic abdominal surgery. These adhesions develop in the weeks following surgery as the body heals.... Read more
Groundbreaking Leadless Pacemaker to Prevent Invasive Surgeries for Children
Leadless pacemakers marked a significant advancement in cardiac care, primarily because traditional pacemakers are dependent on leads, which are prone to breakage over time. Currently, two FDA-approved... Read morePatient Care
view channel
Portable Biosensor Platform to Reduce Hospital-Acquired Infections
Approximately 4 million patients in the European Union acquire healthcare-associated infections (HAIs) or nosocomial infections each year, with around 37,000 deaths directly resulting from these infections,... Read more
First-Of-Its-Kind Portable Germicidal Light Technology Disinfects High-Touch Clinical Surfaces in Seconds
Reducing healthcare-acquired infections (HAIs) remains a pressing issue within global healthcare systems. In the United States alone, 1.7 million patients contract HAIs annually, leading to approximately... Read more
Surgical Capacity Optimization Solution Helps Hospitals Boost OR Utilization
An innovative solution has the capability to transform surgical capacity utilization by targeting the root cause of surgical block time inefficiencies. Fujitsu Limited’s (Tokyo, Japan) Surgical Capacity... Read more
Game-Changing Innovation in Surgical Instrument Sterilization Significantly Improves OR Throughput
A groundbreaking innovation enables hospitals to significantly improve instrument processing time and throughput in operating rooms (ORs) and sterile processing departments. Turbett Surgical, Inc.... Read moreHealth IT
view channel
Printable Molecule-Selective Nanoparticles Enable Mass Production of Wearable Biosensors
The future of medicine is likely to focus on the personalization of healthcare—understanding exactly what an individual requires and delivering the appropriate combination of nutrients, metabolites, and... Read more
Smartwatches Could Detect Congestive Heart Failure
Diagnosing congestive heart failure (CHF) typically requires expensive and time-consuming imaging techniques like echocardiography, also known as cardiac ultrasound. Previously, detecting CHF by analyzing... Read morePoint of Care
view channel
Handheld, Sound-Based Diagnostic System Delivers Bedside Blood Test Results in An Hour
Patients who go to a doctor for a blood test often have to contend with a needle and syringe, followed by a long wait—sometimes hours or even days—for lab results. Scientists have been working hard to... Read more
Smartphone-Enabled, Paper-Based Quantitative Diagnostic Platform Transforms POC Testing
Point-of-care diagnostics are crucial for public health, offering rapid, on-site testing that enables prompt diagnosis and treatment. This is especially valuable in remote or underserved regions where... Read moreBusiness
view channel
Becton Dickinson to Spin Out Biosciences and Diagnostic Solutions Business
Becton, Dickinson and Company (BD, Franklin Lakes, NJ, USA), has announced that its board of directors has unanimously authorized BD management to pursue a plan to separate BD's Biosciences and Diagnostic... Read more