One-Third of Hypertension Patients Noncompliant with Therapy
By Daniel Beris Posted on 16 Nov 2016 |
Image: New research shows one-third of hypertension patients are noncompliant with therapy (Photo courtesy of UNC).
More than 30% of patients with hypertension do not adhere to their antihypertensive drug therapy, according to a new study.
Researchers at the University of North Carolina (UNC, Chapel Hill, USA) conducted a study among 1,826 participants of the Atherosclerosis Risk in Communities Study, who reported hypertension without prevalent cardiovascular disease (CVD) during their annual follow-up calls in 2006 and 2007. Medication adherence was measured as more than 80% proportion days covered, by using Medicare Part D claims. Study outcomes consisted of a composite of cardiovascular events, Medicare inpatient payments, and inpatient days.
The results showed that 31.5% of the participants were noncompliant with their therapy in the three months preceding hypertension reports. Positive predictors included female gender and diabetes; African-American race and current smoking were negative predictors. After adjustment, the correlation between noncompliance and a composite end point of cardiovascular outcomes up to 2012 was not statistically significant, as were adjusted associations with Medicare inpatient days or payments. The study was published on November 3, 2016, in the Journal of Evaluation in Clinical Practice.
“Despite having medical and prescription coverage, nearly a third of hypertensive participants were not adherent to antihypertensive drug therapy,” concluded lead author Jerome Federspiel, MD, PhD. “Differences in clinical outcomes associated with nonadherence, though not statistically significant, were consistent with results from randomized trials.”
The World Health Organization estimates that only 50% of patients with chronic diseases in developed countries follow treatment recommendations. Low rates of adherence for asthma, diabetes, and hypertension are thought to contribute substantially to the human and economic burden of those conditions. Major barriers to compliance include the cost of prescription medicine, complexity of modern medication regimens, poor health literacy and lack of comprehension of treatment benefits, undiscussed side effects, and poor communication or lack of trust between patient and health-care provider.
Related Links:
University of North Carolina
Researchers at the University of North Carolina (UNC, Chapel Hill, USA) conducted a study among 1,826 participants of the Atherosclerosis Risk in Communities Study, who reported hypertension without prevalent cardiovascular disease (CVD) during their annual follow-up calls in 2006 and 2007. Medication adherence was measured as more than 80% proportion days covered, by using Medicare Part D claims. Study outcomes consisted of a composite of cardiovascular events, Medicare inpatient payments, and inpatient days.
The results showed that 31.5% of the participants were noncompliant with their therapy in the three months preceding hypertension reports. Positive predictors included female gender and diabetes; African-American race and current smoking were negative predictors. After adjustment, the correlation between noncompliance and a composite end point of cardiovascular outcomes up to 2012 was not statistically significant, as were adjusted associations with Medicare inpatient days or payments. The study was published on November 3, 2016, in the Journal of Evaluation in Clinical Practice.
“Despite having medical and prescription coverage, nearly a third of hypertensive participants were not adherent to antihypertensive drug therapy,” concluded lead author Jerome Federspiel, MD, PhD. “Differences in clinical outcomes associated with nonadherence, though not statistically significant, were consistent with results from randomized trials.”
The World Health Organization estimates that only 50% of patients with chronic diseases in developed countries follow treatment recommendations. Low rates of adherence for asthma, diabetes, and hypertension are thought to contribute substantially to the human and economic burden of those conditions. Major barriers to compliance include the cost of prescription medicine, complexity of modern medication regimens, poor health literacy and lack of comprehension of treatment benefits, undiscussed side effects, and poor communication or lack of trust between patient and health-care provider.
Related Links:
University of North Carolina
Latest Critical Care News
- Powerful AI Risk Assessment Tool Predicts Outcomes in Heart Failure Patients
- Peptide-Based Hydrogels Repair Damaged Organs and Tissues On-The-Spot
- One-Hour Endoscopic Procedure Could Eliminate Need for Insulin for Type 2 Diabetes
- AI Can Prioritize Emergency Department Patients Requiring Urgent Treatment
- AI to Improve Diagnosis of Atrial Fibrillation
- Stretchable Microneedles to Help In Accurate Tracking of Abnormalities and Identifying Rapid Treatment
- Machine Learning Tool Identifies Rare, Undiagnosed Immune Disorders from Patient EHRs
- On-Skin Wearable Bioelectronic Device Paves Way for Intelligent Implants
- First-Of-Its-Kind Dissolvable Stent to Improve Outcomes for Patients with Severe PAD
- AI Brain-Age Estimation Technology Uses EEG Scans to Screen for Degenerative Diseases
- Wheeze-Counting Wearable Device Monitors Patient's Breathing In Real Time
- Wearable Multiplex Biosensors Could Revolutionize COPD Management
- New Low-Energy Defibrillation Method Controls Cardiac Arrhythmias
- New Machine Learning Models Help Predict Heart Disease Risk in Women
- Deep-Learning Model Predicts Arrhythmia 30 Minutes before Onset
- Breakthrough Technology Combines Detection and Treatment of Nerve-Related Disorders in Single Procedure