Living Donor Liver Transplantation Relatively Safe
By HospiMedica International staff writers Posted on 29 Jul 2014 |
A new study shows that right liver lobe donor hepatectomy can be performed with minimal complication rates, increasing the potential donor pool dramatically.
Researchers at Afyon Kocatepe University (AKU; Afyon, Turkey), Ege University (Izmir, Turkey), and International Kent Hospital (Izmir, Turkey) conducted a study to determine the rate of complications associated with surgery in 272 living donors (57.4% male) who underwent right lobe donor hepatectomy between September 2004 and December 2009, after passing an elimination system. Demographic data, intraoperative findings, and complication rates were collected retrospectively. Donor complications were categorized according to the Clavien classification.
The results showed that there was no donor mortality. Grade 1 and 2 complications were observed in 105 (38%) of the donors, with the most common complications being fever of unknown origin and prolonged hyperbilirubinemia. Grade 3 and grade 4 complications were observed in 6 donors (2%) and 3 donors (1%), respectively. Three donors underwent re-operation due to bleeding, with a re-laparatomy rate of 1.10%. One donor—categorized as grade 4B—suffered a small bowel perforation and intra-abdominal sepsis secondary to mechanical bowel obstruction. The study was published in the June 2014 issue of Transplantation Proceedings.
“Living donor liver transplantation has been a new light of hope for patients with end-stage liver failure on the cadaveric waiting list,” concluded lead author Mustafa Ozsoy, MD, and colleagues. “Right liver lobe donor hepatectomy can be performed successfully with minimal complication rates with multidisciplinary and rigorous donor care in the preoperative and postoperative period.”
Traditionally, organs for liver transplant are obtained from deceased donors; unfortunately, there are not enough deceased donor organs available for today's growing list of people who are waiting for one. In a live donor liver transplant, one lobe is removed and transplanted immediately after the recipient's liver has been entirely removed. Live donor liver transplantation is possible because the liver, unlike any other organ in the body, has the ability to regenerate, usually within a period of 4 to 8 weeks after surgery.
Related Links:
Afyon Kocatepe University
Ege University
International Kent Hospital
Researchers at Afyon Kocatepe University (AKU; Afyon, Turkey), Ege University (Izmir, Turkey), and International Kent Hospital (Izmir, Turkey) conducted a study to determine the rate of complications associated with surgery in 272 living donors (57.4% male) who underwent right lobe donor hepatectomy between September 2004 and December 2009, after passing an elimination system. Demographic data, intraoperative findings, and complication rates were collected retrospectively. Donor complications were categorized according to the Clavien classification.
The results showed that there was no donor mortality. Grade 1 and 2 complications were observed in 105 (38%) of the donors, with the most common complications being fever of unknown origin and prolonged hyperbilirubinemia. Grade 3 and grade 4 complications were observed in 6 donors (2%) and 3 donors (1%), respectively. Three donors underwent re-operation due to bleeding, with a re-laparatomy rate of 1.10%. One donor—categorized as grade 4B—suffered a small bowel perforation and intra-abdominal sepsis secondary to mechanical bowel obstruction. The study was published in the June 2014 issue of Transplantation Proceedings.
“Living donor liver transplantation has been a new light of hope for patients with end-stage liver failure on the cadaveric waiting list,” concluded lead author Mustafa Ozsoy, MD, and colleagues. “Right liver lobe donor hepatectomy can be performed successfully with minimal complication rates with multidisciplinary and rigorous donor care in the preoperative and postoperative period.”
Traditionally, organs for liver transplant are obtained from deceased donors; unfortunately, there are not enough deceased donor organs available for today's growing list of people who are waiting for one. In a live donor liver transplant, one lobe is removed and transplanted immediately after the recipient's liver has been entirely removed. Live donor liver transplantation is possible because the liver, unlike any other organ in the body, has the ability to regenerate, usually within a period of 4 to 8 weeks after surgery.
Related Links:
Afyon Kocatepe University
Ege University
International Kent Hospital
Latest Surgical Techniques News
- Miniaturized Implantable Multi-Sensors Device to Monitor Vessels Health
- Tiny Robots Made Out Of Carbon Could Conduct Colonoscopy, Pelvic Exam or Blood Test
- Miniaturized Ultrasonic Scalpel Enables Faster and Safer Robotic-Assisted Surgery
- AI Assisted Reading Tool for Small Bowel Video Capsule Endoscopy Detects More Lesions
- First-Ever Contact Force Pulsed Field Ablation System to Transform Treatment of Ventricular Arrhythmias
- Caterpillar Robot with Built-In Steering System Crawls Easily Through Loops and Bends
- Tiny Wraparound Electronic Implants to Revolutionize Treatment of Spinal Cord Injuries
- Small, Implantable Cardiac Pump to Help Children Awaiting Heart Transplant
- Gastrointestinal Imaging Capsule a Game-Changer in Esophagus Surveillance and Treatment
- World’s Smallest Laser Probe for Brain Procedures Facilitates Ablation of Full Range of Targets
- Artificial Intelligence Broadens Diagnostic Abilities of Conventional Coronary Angiography
- AI-Powered Surgical Visualization Tool Supports Surgeons' Visual Recognition in Real Time
- Cutting-Edge Robotic Bronchial Endoscopic System Provides Prompt Intervention during Emergencies
- Handheld Device for Fluorescence-Guided Surgery a Game Changer for Removal of High-Grade Glioma Brain Tumors
- Porous Gel Sponge Facilitates Rapid Hemostasis and Wound Healing
- Novel Rigid Endoscope System Enables Deep Tissue Imaging During Surgery