Preoperative Brain Mapping Can Protect Language Centers
By HospiMedica International staff writers Posted on 22 Jul 2020 |
Image: Stimulating the brain with rapid magnetic pulses helps determine language center locations (Photo courtesy of Kazuya Motomura/ Nagoya University)
A new study shows that mapping language centers via navigated repetitive transcranial magnetic stimulation (nrTMS) before brain surgery could help improve surgical planning.
Researchers at Nagoya University School of Medicine (Japan) conducted a prospective, non-randomized study involving 61 adult patients (39 men, 22 women; mean age 41.1 years), which included 42 low-grade gliomas and 19 high-grade gliomas. Inclusion criteria included the presence of left- or right-side brain tumors in the vicinity of or inside areas anatomically associated with language functions, and scheduled awake brain surgery. Prior to surgery, rapid nrTMS was applied while the patient named images; when they failed, the language center was detected.
The results showed that the tumor was located in the left hemisphere in 50 (82%) of the patients, and in the right hemisphere in 11 (18%). In the 50 patients with left-side gliomas, the factor that significantly impacted nrTMS mapping accuracy in the language center was tumor involvement; otherwise, nrTMS showed a good degree of reliability. The scientists also successfully used nrTMS to determine the side of the brain where the language center is mainly located in each patient. The study was published on June 3, 2020, in Scientific Reports.
“Subgroup analysis showed that the non-involvement of language-related regions afforded significantly better the area under the curve values than the involvement of language-related regions,” concluded lead author neurosurgeon Kazuya Motomura, MD. “Our findings suggest that nrTMS language mapping could be a reliable method, particularly in obtaining responses for cases without tumor-involvement of classical perisylvian language areas.”
Transcranial magnetic stimulation is a noninvasive method to cause depolarization or hyperpolarization in the neurons of the brain via electromagnetic induction to induce weak electric currents using a rapidly changing magnetic field.
Related Links:
Nagoya University School of Medicine
Researchers at Nagoya University School of Medicine (Japan) conducted a prospective, non-randomized study involving 61 adult patients (39 men, 22 women; mean age 41.1 years), which included 42 low-grade gliomas and 19 high-grade gliomas. Inclusion criteria included the presence of left- or right-side brain tumors in the vicinity of or inside areas anatomically associated with language functions, and scheduled awake brain surgery. Prior to surgery, rapid nrTMS was applied while the patient named images; when they failed, the language center was detected.
The results showed that the tumor was located in the left hemisphere in 50 (82%) of the patients, and in the right hemisphere in 11 (18%). In the 50 patients with left-side gliomas, the factor that significantly impacted nrTMS mapping accuracy in the language center was tumor involvement; otherwise, nrTMS showed a good degree of reliability. The scientists also successfully used nrTMS to determine the side of the brain where the language center is mainly located in each patient. The study was published on June 3, 2020, in Scientific Reports.
“Subgroup analysis showed that the non-involvement of language-related regions afforded significantly better the area under the curve values than the involvement of language-related regions,” concluded lead author neurosurgeon Kazuya Motomura, MD. “Our findings suggest that nrTMS language mapping could be a reliable method, particularly in obtaining responses for cases without tumor-involvement of classical perisylvian language areas.”
Transcranial magnetic stimulation is a noninvasive method to cause depolarization or hyperpolarization in the neurons of the brain via electromagnetic induction to induce weak electric currents using a rapidly changing magnetic field.
Related Links:
Nagoya University School of Medicine
Latest Surgical Techniques News
- Miniaturized Implantable Multi-Sensors Device to Monitor Vessels Health
- Tiny Robots Made Out Of Carbon Could Conduct Colonoscopy, Pelvic Exam or Blood Test
- Miniaturized Ultrasonic Scalpel Enables Faster and Safer Robotic-Assisted Surgery
- AI Assisted Reading Tool for Small Bowel Video Capsule Endoscopy Detects More Lesions
- First-Ever Contact Force Pulsed Field Ablation System to Transform Treatment of Ventricular Arrhythmias
- Caterpillar Robot with Built-In Steering System Crawls Easily Through Loops and Bends
- Tiny Wraparound Electronic Implants to Revolutionize Treatment of Spinal Cord Injuries
- Small, Implantable Cardiac Pump to Help Children Awaiting Heart Transplant
- Gastrointestinal Imaging Capsule a Game-Changer in Esophagus Surveillance and Treatment
- World’s Smallest Laser Probe for Brain Procedures Facilitates Ablation of Full Range of Targets
- Artificial Intelligence Broadens Diagnostic Abilities of Conventional Coronary Angiography
- AI-Powered Surgical Visualization Tool Supports Surgeons' Visual Recognition in Real Time
- Cutting-Edge Robotic Bronchial Endoscopic System Provides Prompt Intervention during Emergencies
- Handheld Device for Fluorescence-Guided Surgery a Game Changer for Removal of High-Grade Glioma Brain Tumors
- Porous Gel Sponge Facilitates Rapid Hemostasis and Wound Healing
- Novel Rigid Endoscope System Enables Deep Tissue Imaging During Surgery