Antimicrobial Coatings Reduce Implant Endotoxin Contamination
By HospiMedica International staff writers Posted on 23 Feb 2021 |
Image: SEM images of conformal ALD coating on the edges and corners of Silicone (Photo courtesy of Picosun)
Advanced atomic layer deposition (ALD) thin film coating technology reduces microbial growth by hermetically encapsulating implanted devices.
The Picosun (Espoo, Finland) AGILE ultra-thin ALD coatings are designed to ensure pinhole-free coverage over even the smallest parts of an implanted device. The ALD coating impedes microbial adherence to implants, resulting in low values of bacterial endotoxin deposit. The thin film ALD coating is intrinsically biocompatible and remains inert inside the human body, uniformly covering even complex three dimensional (3D) structures with nanoscale details, such as micro-scale neural stimulators, diagnostic sensors, and more. The coating can also be applied to larger items, such as hip, knee, and dental implants.
In addition, the ALD coating completely blocks the diffusion of Na+, K+, Cl– and PO43- ions, which are known to be amongst the most corrosive ionic species in aqueous media, extending the lifetime and operational reliability of the implants, and reducing the need for corrective or replacement surgeries, thus improving the patient's quality of life. ALD oxide coating for medical implants include TiO2, Al2O3, HfO2, SiO2, ZrO2, Nb2O5, Ta2O5, AlN and TiN ALD films.
“ALD’s excellent barrier properties either as such, or combined with other encapsulation methods, support the trend of miniaturization and increased functionalization of medical microelectronics and enable a variety of novel products,” said Jani Kivioja, PhD, CTO of Picosun Group. “Introduction of ALD encapsulation can also help the manufacturers to replace expensive, noble metal components with cheaper materials, when ALD protection ensures the inertness of the devices inside the body.”
ALD is a thin-film deposition technique based on sequential use of gas phase chemical vapor deposition. The majority of ALD reactions use two chemicals precursors that react with the surface of a material one at a time in a sequential, self-limiting, manner. Through the repeated exposure to separate precursors, a thin film is slowly deposited. ALD is a key process in the fabrication of semiconductor devices, and part of the set of tools available for the synthesis of nanomaterials. ALD coatings can be applied at relatively low temperatures, which advocates their use also on sensitive materials such as plastics and polymers.
Related Links:
Picosun
The Picosun (Espoo, Finland) AGILE ultra-thin ALD coatings are designed to ensure pinhole-free coverage over even the smallest parts of an implanted device. The ALD coating impedes microbial adherence to implants, resulting in low values of bacterial endotoxin deposit. The thin film ALD coating is intrinsically biocompatible and remains inert inside the human body, uniformly covering even complex three dimensional (3D) structures with nanoscale details, such as micro-scale neural stimulators, diagnostic sensors, and more. The coating can also be applied to larger items, such as hip, knee, and dental implants.
In addition, the ALD coating completely blocks the diffusion of Na+, K+, Cl– and PO43- ions, which are known to be amongst the most corrosive ionic species in aqueous media, extending the lifetime and operational reliability of the implants, and reducing the need for corrective or replacement surgeries, thus improving the patient's quality of life. ALD oxide coating for medical implants include TiO2, Al2O3, HfO2, SiO2, ZrO2, Nb2O5, Ta2O5, AlN and TiN ALD films.
“ALD’s excellent barrier properties either as such, or combined with other encapsulation methods, support the trend of miniaturization and increased functionalization of medical microelectronics and enable a variety of novel products,” said Jani Kivioja, PhD, CTO of Picosun Group. “Introduction of ALD encapsulation can also help the manufacturers to replace expensive, noble metal components with cheaper materials, when ALD protection ensures the inertness of the devices inside the body.”
ALD is a thin-film deposition technique based on sequential use of gas phase chemical vapor deposition. The majority of ALD reactions use two chemicals precursors that react with the surface of a material one at a time in a sequential, self-limiting, manner. Through the repeated exposure to separate precursors, a thin film is slowly deposited. ALD is a key process in the fabrication of semiconductor devices, and part of the set of tools available for the synthesis of nanomaterials. ALD coatings can be applied at relatively low temperatures, which advocates their use also on sensitive materials such as plastics and polymers.
Related Links:
Picosun
Latest Surgical Techniques News
- Porous Gel Sponge Facilitates Rapid Hemostasis and Wound Healing
- Novel Rigid Endoscope System Enables Deep Tissue Imaging During Surgery
- Robotic Nerve ‘Cuffs’ Could Treat Various Neurological Conditions
- Flexible Microdisplay Visualizes Brain Activity in Real-Time To Guide Neurosurgeons
- Next-Gen Computer Assisted Vacuum Thrombectomy Technology Rapidly Removes Blood Clots
- Hydrogel-Based Miniaturized Electric Generators to Power Biomedical Devices
- Custom 3D-Printed Orthopedic Implants Transform Joint Replacement Surgery
- Wearable Technology Monitors and Analyzes Surgeons' Posture during Long Surgical Procedures
- Cutting-Edge Imaging Platform Detects Residual Breast Cancer Missed During Lumpectomy Surgery
- Computational Models Predict Heart Valve Leakage in Children
- Breakthrough Device Enables Clear and Real-Time Visual Guidance for Effective Cardiovascular Interventions
- World’s First Microscopic Probe to Revolutionize Early Cancer Diagnosis
- World’s Smallest Implantable Brain Stimulator Demonstrated in Human Patient
- Robotically Assisted Lung Transplants Could Soon Become a Reality
- AI to Provide Heart Transplant Surgeons with New Decision-Making Data
- New Surgical Tool Empowers Precision and Confidence in Operating Room